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Phenytoin overdose

Definition:

Phenytoin overdose is poisoning from an overdose of phenytoin.



Alternative Names: Diphenylhydantoin

Poisonous Ingredient:

Diphenylhydantoin (Phenytoin)



Where Found:
  • Dilantin
  • Antisacer
  • Dintoina
  • Diphenylan Sodium
  • Epanutin
  • Fenytoin

This list may not be all-inclusive.



Symptoms:

Home Treatment:

Contact Poison Control for instructions.



Before Calling Emergency:

Determine the following information:

  • The patient's age, weight, and condition
  • Name of product (as well as the ingredients and strength if known)
  • The time it was swallowed
  • The amount swallowed
  • If the medication was prescribed for the patient


Poison Control, or a local emergency number:

They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.



What to expect at the emergency room:

Some or all of the following may be performed or given:

  • Maintaining the airway
  • Maintaining breathing
  • Activated charcoal
  • Laxative
  • Gastric lavage
  • Close observation
  • Monitoring of�phenytoin blood levels
  • Treatment of�other symptoms


Expectations (prognosis):
  • Mild overdose (no treatment is necessary):
    • The patient can be aroused.
  • Moderate overdose (recovery is usually within 24�- 48 hours with proper treatment):
    • The patient cannot be aroused, but vital functions are normal.
  • Severe overdose (a 3�- 5 day period may be required before the patient recovers, and fatality rate is less than 5%):



Review Date: 5/10/2005
Reviewed By: William D. Whetstone, M.D., Division of Emergency Medicine, University of California San Francisco, San Francisco, CA. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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114 Woodland Street
Hartford, Connecticut 06105
(860) 714-4000

 
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